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List of abbreviations AAPSCQIM American Academy of Pediatrics Steering Committee on Quality Improvement and Managements A β 1− 42 Beta-amyloid ACE2 Angiotensin Converting Enzyme 2 AD Alzheimer’s disease ADAS-Cog Alzheimer’s Disease ADD Alzheimer’s disease dementia ADHD Attention deficit/hyperactivity disorder AERD Aspirin-Exacerbated Respiratory Disease AHSP Appetite, Hunger and Sensory perception ADLB Alzheimer’s dementia with Lewy bodies AES Apathy Evaluation Scale ALS Amyotrophic lateral sclerosis ALS-N ALS with normal cognition AMG Amygdala aMCI amnestic mild cognitive impairment AN Animal naming test or Anorexia Nervosa AR Allergic rhinitis AROMA Affordable, Rapid, Olfactory Measurement Array ART Akinetic-Rigid Type ASA Aspirin Desensitization Therapy AS-Cog Assessment Scale-Cognition ASD Autism Spectrum Disorder α -syn alpha-synuclein protein BAST-24 Barcelona Smell Test BAI Beck Anxiety Inventory BBB Blood Brain Barrier BD Behcet’s disease BDI Beck Depression Inventory BED Binge Easting Disorder bFGF basic fibroblast growth factor BICAMS The Brief International Cognitive Assessment for MS BMI Body Mass Index BMS burning mouth syndrome BNT Boston Naming Test BOLD Blood oxygen level-dependent signal BOMCT Blessed Orientation Memory Concentration Test BPD Bipolar Disorder BSG basigin B-SITR ® Brief Smell Identification Test (also known as the Cross-Cultural Smell Identification Test or CC-SIT) BTT Butanol threshold test BVMT Brief Visuospatial Memory Test CA Congenital anosmia CAMCOG Cambridge Examination for Mental Disorders in the Elderly cAMP cyclic adenosine monophosphate CASI Cognitive Abilities Screening Instrument CCCRC Connecticut Clinical Chemosensory Research Center test CCL chemokine ligand CCR chemokine receptor CD Cognitive decline CDKN2A/P16INK4a Cyclin-dependent kinase inhibitor 2A/P16 CFD computational fluid dynamics cGMP cyclic guanine monophosphate ChE Cholinesterase CHH congenital hypogonatropic hypogonadism CI Cognitive impairment CLC Charcot Leyden crystal protein CN I Cranial nerve one CNS Central Nervous System COT Classic olfactory training COMB Combination COVID-19 coronavirus disease 2019 COWAT Controlled Oral Word Association Test CPG Clinical Practice Guideline CR Chronic Rhinitis CRP C-reactive protein CRS Chronic rhinosinusitis CRSsNP Chronic rhinosinusitis without nasal polyps CRSwNP Chronic rhinosinusitis with nasal polyps CSF Cerebrospinal fluid CSIT 40-item Chinese Smell Identification Test CSQ Chemosensory questionnaire CT Computerized tomography CVLT II California Verbal Learning Test-II CXCL chemokine (C-X-C motif) ligand D CFL: Category Fluency: Discrimination DAT Dopamine transporter DHA docosahexanoic acid DISC Discrimination DIP Drug-induced Parkinsonism DLB Dementia with Lewy bodies DM Diabetes mellitus DMT disease-modifying therapy DODT Disseldorf Odour Discrimination Test DRS Dementia Rating Scale DT Detection threshold DTI Diffusion tensor imaging EBM Evidence Based Medicine EBR Evidence Based Review EBRR Evidence Based Review with Recommendations ECP Eosinophilic cationic protein EDSS Expanded Disability Status Scale EEA Endoscopic endonasal approach EHLS Epidemiology of Hearing Loss Study EMBASE Excerpta Medica database EO-PD Early-onset PD EOG Electro-olfactogram ERP Event-related potential ETTH Episodic tension type headache ESS Endoscopic sinus surgery F Female FA Fractional Anisotropy FAB Frontal Assessment Battery FDA Federal Drug Administration FDG 18 F-2-fluoro-2-deoxy-D-glucose FFQ Food-Frequency Questionnaire FG Fusiform gyrus FH Family history fMRI Functional magnetic resonance imaging FP Fluticasone propionate FTD Frontotemporal dementia FTG Fusiform gyrus FTG-PET Positron emission tomography using the radiopharmaceutical fluorodeoxyglucose GAD-7 Generalized Anxiety Disorder GCS Glasgow Coma Scale GM Gray matter GM-CSF Granulocyte monocyte-colony stimulating factor GPA Granulomatosis with Polyangiitis HAND HIV-associated neurocognitive disorders HARS Hamilton Anxiety Rating Scale HBC Horizontal basal cells HC Healthy controls HD Huntington’s disease HDRS Hamilton Depression Rating Scale Hipp Hippocampus HLA Human Leukocyte Antigen HNC Head and Neck Cancer HRSL Hyposmia Rating Scale HRV Heart rate variability HWM Heavy Weight Molecules ICA Isolated congenital anosmia ICAR:O International Consensus Statement on Allergy and Rhinology: Olfaction ICD Intracranial disease ICHD International Classification of Headache Disorders ID Identification IFG Inferior frontal gyrus IFN-γ interferon gamma IgG4RD Immunoglobulin G4 – related disease IgE Immunoglobulin E IL interleukin ILB Incidental Lewy Bodies IMRT Intensity-modulated radiotherapy KS Kallmann syndrome LARK2 Leucine-Rich Repeat Kinase 2 gene LASA Longitudinal Aging Study Amsterdam LCPUFA long chain polyunsaturated fatty acids LOE Level of Evidence LO-PD IMC Information-Memory-Concentration Test for Late-onset PD LOT-R Life Orientation Test LR Literature Review LS Loneliness Scale LWM Light Weight Molecules M Male M cells Mitral cells MA Migraine with aura MC Mutation carrier MCI Mild cognitive impairment MCID Minimal clinically important difference Multi-Clinic Smell and Taste Questionnaire-Scandanavian (MCSTQ-Sc) MczD Mikulicz’s disase MD Major depression MDD Major depressive disorder MDI Major depression inventory MEDLINE Medical Literature Analysis and Retrieval System Online MFI Modified Fatigue Impact MG Myasthenia gravis MHC Major Histocompatability Complex MIBG 123 I-meta-iodobenzylguanidine MITG Middle/Inferior temporal gyri MMSE Mini-Mental State Examination MO Migraine without aura MOA Monoamine MOCA Montreal Cognitive Assessment MP Methylprednisolone MPS Mild Parkinsonian signs MPTP 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine MRI Magnetic Resonance Imaging MSA Multiple System Atrophy MTC Medial temporal cortex MND Motor neuron disease MS Multiple Sclerosis MSSS Multiple Sclerosis Severity Score MTHFR methyl tetra folate reductase enzyme mutation MultD Multiple cognitive domain naMCI non-amnestic mild cognitive impairment N Nuclear Factor NAR Non-Allergic Rhinitis ND Neurodegenerative disease NDE Plasma neuronal-derived exosome NE Normal elderly NDE AB 1–42 Plasma neural-derived exosome amyloid beta peptide 42 NHANES U.S

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